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Questions : 1. What is the abnormality ? 2. Explain the low values in spirometry and diffusion
Age : 34 Race : W Height : 68 in (173 cm) Weight: 133lb(60 kg)
Spirometry Predicted Range Observed Pre %Pred FVC 4.78 - 2.83 2.23 46 SVC 4.78 - 2.83 2.31 48 FEV1 3.98 - 2.3 1.44 36 FEV1/FVC 82.87 - 74.57 64.58 77 FEF25-75 4.25 - 1.9 .81 19 PEFR 543 - 309 313 57 FEV1/PEFR 7.3 - 7.4 4.5 62 PEFR/PIFR 1.4 - 1.3 1.3 91 FEF25 8.39 - 4.63 2.78 33 FEF50 5.03 - 2.35 .95 18 FEF75 2.09 - .63 .26 12 FET 4.78 - 2.83 4.31 FIVC - 2.19 45 PIFR 362 - 227 62 FIF50 - 3.14
Lung Volumes SVC 4.78 - 2.83 2.31 48 FRC 3.17 - 1.71 1.89 59 IC 3.21 - 2.04 1.15 35 ERV 1.57 - .13 1.16 73 RV 1.59 - .83 .73 45 TLC 6.38 - 4.78 3.04 47 RV/ TLC 24.57 - 15.77 23.99 97
Note: These lung volumes measured by a Helium dilution technique
Diffusion Tlco sb 31.87 - 29.00 13.51 42 Va Btps 7.29 - 5.68 2.48 34 Va 6.51 - 4.9 2.06 31 KCO 5.26 - 3.92 5.46 103 DLCO variables: Vol Insp litres 1.54 Vol Btps litres 1.67
Answers - please attempt to answer the quiz yourself before reading the answers!
Question 1. What is the abnormality ? Answer : Low diffusion factor but well preserved KCO Low FEV1 + FVC Restrictive defect
Question 2. Explain the low values in spirometry and diffusion Answer : Small lungs, could be explained by weak muscles e.g. MND or by musculo-skeletal deformity eg kyphoscoliosis Less likely to be caused by pulmonary infiltration / fibrosis because of the well preserved KCO.
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